Apple cider vinegar suppresses obesity-induced oxidative stress

In obese individuals, oxidative stress increases the risk of developing cardiovascular disease, among other health conditions. A study published in the Journal of Medicinal Food found that the daily intake of apple cider vinegar can have beneficial effects against both oxidative stress and the risk of heart- and blood vessel-related conditions.

  • The researchers noted that although natural antioxidants can help attenuate oxidative stress, synthetic antioxidants used in many supplements could be contraindicative.
  • They used an animal model composed of rats with a high-fat diet (HFD)-induced obesity. The animals showed increases in serum total cholesterol, triglyceride, low-density lipoprotein-cholesterol (LDL-C), very low-density lipoprotein (VLDL) and atherogenic index six and nine weeks after they were fed the HFD. Oxidative stress had also developed six weeks after the feeding started.
  • The administration of apple cider vinegar was noted to have decreased all parameters for cardiovascular disease. The treatment also reduced the levels of malondialdehyde while improving the animals’ antioxidant status, suggesting a reversal of oxidative stress.
  • When compared with the HFD group, the animals treated with apple cider vinegar showed a modulation in trace element levels.

The researchers concluded that apple cider vinegar can help reverse the changes in oxidant-antioxidant balance caused by an HFD. Apple cider vinegar can also modulate the antioxidant defense system to suppress oxidative stress that originates from obesity. It can also reduce the risk of cardiovascular disease by preventing atherogenic risk.

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Journal Reference:

Halima BH, Sonia G, Sarra K, Houda BJ, Fethi BS, Abdallah A. APPLE CIDER VINEGAR ATTENUATES OXIDATIVE STRESS AND REDUCES THE RISK OF OBESITY IN HIGH-FAT-FED MALE WISTAR RATS. Journal of Medicinal Food. 1 January 2018;21(1):70–80. DOI: 10.1089/jmf.2017.0039

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